Description

Mucin-1 (MUC1). Can act both as an adhesion and an anti-adhesion protein. May provide a protective layer on epithelial cells against bacterial and enzyme attack. Promotes tumor progression.


Clinical trials

NCT03356795 - Cervical Cancer
NCT02839954 - Colorectal Carcinoma, Hepatocellular Carcinoma, Pancreatic Carcinoma
NCT02617134 - Colorectal Carcinoma
NCT02587689 - Hepatocellular Carcinoma, Pancreatic Carcinoma
NCT04025216 - Ovarian Cancer
NCT03267173 - Pancreatic Carcinoma


Target gene expression

The following plot describes the expression, in different tissues and TCGA cancers, of the different isoforms of the gene MUC1.


Target essentiality


Protein properties

The following plot describes the target topology, highlighting the position of the endo-, ecto- and transmembrane domains, as well as the position of a signal peptide, when present. The last three rows describe the position of potential epitopes, as well as phosphorylation and glycosylation sites.